| Player | Runs | Balls | 4s | 6s | SR | Opposition | Ground | Match Date |
|---|---|---|---|---|---|---|---|---|
| Inzamam-ul-Haq | 329 | 436 | 38 | 9 | 75.46 | New Zealand | Lahore | 01 May 2002 |
| Younis Khan | 313 | 568 | 27 | 4 | 55.11 | Sri Lanka | Karachi | 21 Feb 2009 |
| Azhar Ali | 302 | 469 | 23 | 2 | 64.39 | West Indies | Dubai (DSC) | 13 Oct 2016 |
| Javed Miandad | 280 | 460 | 19 | 1 | 60.87 | India | Hyderabad (Sind) | 14 Jan 1983 |
| Zaheer Abbas | 274 | 467 | 38 | 0 | 58.67 | England | Birmingham | 03 Jun 1971 |
| Javed Miandad | 271 | 465 | 28 | 5 | 58.28 | New Zealand | Auckland | 24 Feb 1989 |
| Younis Khan | 267 | 504 | 32 | 1 | 52.98 | India | Bengaluru | 24 Mar 2005 |
| Javed Miandad | 260 | 521 | 28 | 1 | 49.90 | England | The Oval | 06 Aug 1987 |
| Wasim Akram | 257 | 363 | 22 | 12 | 70.80 | Zimbabwe | Sheikhupura | 17 Oct 1996 |
| Shoaib Malik | 245 | 420 | 24 | 4 | 58.33 | England | Abu Dhabi | 13 Oct 2015 |
| Zaheer Abbas | 240 | 410 | 22 | 0 | 58.54 | England | The Oval | 22 Aug 1974 |
| Saleem Malik | 237 | 328 | 34 | 0 | 72.26 | Australia | Rawalpindi | 05 Oct 1994 |
| Taufeeq Umar | 236 | 496 | 17 | 1 | 47.58 | Sri Lanka | Abu Dhabi | 18 Oct 2011 |
| Zaheer Abbas | 235 | 0 | 29 | 2 | 0.00 | India | Lahore | 27 Oct 1978 |
| Mudassar Nazar | 231 | 444 | 21 | 1 | 52.03 | India | Hyderabad (Sind) | 14 Jan 1983 |
| Azhar Ali | 226 | 428 | 20 | 2 | 52.80 | Bangladesh | Dhaka | 06 May 2015 |
| Mohammad Hafeez | 224 | 332 | 23 | 3 | 67.47 | Bangladesh | Khulna | 28 Apr 2015 |
| Mohammad Yousuf | 223 | 373 | 26 | 2 | 59.79 | England | Lahore | 29 Nov 2005 |
| Younis Khan | 218 | 308 | 31 | 4 | 70.78 | England | The Oval | 11 Aug 2016 |
| Zaheer Abbas | 215 | 254 | 23 | 2 | 84.65 | India | Lahore | 10 Dec 1982 |
| Younis Khan | 213 | 349 | 15 | 2 | 61.03 | Australia | Abu Dhabi | 30 Oct 2014 |
| Ijaz Ahmed | 211 | 372 | 23 | 1 | 56.72 | Sri Lanka | Dhaka | 12 Mar 1999 |
| Javed Miandad | 211 | 441 | 29 | 1 | 47.85 | Australia | Karachi | 15 Sep 1988 |
| Qasim Umar | 210 | 442 | 27 | 0 | 47.51 | India | Faisalabad | 24 Oct 1984 |
| Taslim Arif | 210 | 379 | 20 | 0 | 55.41 | Australia | Faisalabad | 06 Mar 1980 |
| Qasim Umar | 206 | 0 | 0 | 0 | 0.00 | Sri Lanka | Faisalabad | 16 Oct 1985 |
| Javed Miandad | 206 | 0 | 29 | 2 | 0.00 | New Zealand | Karachi | 30 Oct 1976 |
| Azhar Ali | 205 | 364 | 20 | 0 | 56.32 | Australia | Melbourne | 26 Dec 2016 |
| Aamer Sohail | 205 | 284 | 32 | 0 | 72.18 | England | Manchester | 02 Jul 1992 |
| Shoaib Mohammad | 203 | 411 | 23 | 0 | 49.39 | New Zealand | Karachi | 10 Oct 1990 |
| Shoaib Mohammad | 203 | 338 | 20 | 0 | 60.06 | India | Lahore | 01 Dec 1989 |
| Javed Miandad | 203 | 0 | 0 | 1 | 0.00 | Sri Lanka | Faisalabad | 16 Oct 1985 |
| Mohammad Yousuf | 202 | 330 | 26 | 1 | 61.21 | England | Lord's | 13 Jul 2006 |
| Mushtaq Mohammad | 201 | 0 | 20 | 0 | 0.00 | New Zealand | Dunedin | 07 Feb 1973 |
| Younis Khan | 200 | 404 | 15 | 3 | 49.50 | Zimbabwe | Harare | 03 Sep 2013 |
| Younis Khan | 200 | 290 | 18 | 3 | 68.97 | Bangladesh | Chittagong | 09 Dec 2011 |
| Inzamam-ul-Haq | 200 | 397 | 23 | 2 | 50.38 | Sri Lanka | Dhaka | 12 Mar 1999 |
| Mohsin Khan | 200 | 386 | 23 | 0 | 51.81 | England | Lord's | 12 Aug 1982 |
| Younis Khan | 199 | 336 | 26 | 0 | 59.23 | India | Lahore | 13 Jan 2006 |
| Mudassar Nazar | 199 | 408 | 24 | 0 | 48.77 | India | Faisalabad | 24 Oct 1984 |
| Mohammad Hafeez | 197 | 316 | 25 | 3 | 62.34 | New Zealand | Sharjah | 26 Nov 2014 |
| Mohammad Hafeez | 196 | 331 | 20 | 1 | 59.21 | Sri Lanka | Colombo (SSC) | 30 Jun 2012 |
| Younis Khan | 194 | 299 | 22 | 1 | 64.88 | India | Faisalabad | 21 Jan 2006 |
| Haris Sohail | 147 | 421 | 13 | 0 | 34.92 | New Zealand | Dubai International Cricket Stadium | 24 Nov 2018 |
| Azhar Ali | 134 | 297 | 12 | 0 | 45.12 | New Zealand | Sheikh Zayed Stadium | 03 Dec 2018 |
| Babar Azam | 127 | 263 | 12 | 2 | 48.29 | New Zealand | Dubai International Cricket Stadium | 24 Nov 2018 |
| Asad Shafiq | 104 | 259 | 14 | 0 | 40.15 | New Zealand | Sheikh Zayed Stadium | 03 Dec 2018 |
| Asad Shafiq | 88 | 118 | 12 | 1 | 74.58 | South Africa | 03 Jan 2019 | |
| Azhar Ali | 81 | 187 | 7 | 1 | 43.32 | New Zealand | Dubai International Cricket Stadium | 24 Nov 2018 |
| Babar Azam | 72 | 87 | 15 | 0 | 82.76 | South Africa | 03 Jan 2019 |
