England's 'cursed' tour of South Africa continued on Thursday after opening batsman Rory Burns was ruled out for the remainder of the four-Test series with an ankle injury sustained while playing football.

The loss of Burns for the second Test at Newlands starting on Friday is a major blow for the tourists, who have also had 17 players and support staff laid low with flu during the series.

"Opening batsman Rory Burns has sustained ligament damage to his left ankle," the England and Wales Cricket Board (ECB) said in a statement. "He has been ruled out of the remainder of the South Africa test series and will return home for further assessment and treatment at the earliest convenience."

Burns, 29, top-scored for England with 84 in the second innings of their 107-run defeat in the first Test and looked assured on a difficult wicket. He was injured playing a game of football as a warm-up to training on Thursday.

It is not the first time England have lost a key player during their warm-up games of football. Wicketkeeper-batsman Jonny Bairstow was injured in Sri Lanka in 2018, which prompted England's director of cricket Ashley Giles to suggest the games should be stopped.