Naseem played the first game of the T20I series while Shadab rested in all four games at National Stadium in Karachi
Pakistan is likely to play their best side in the remaining three games of the T20I series against England at Gaddafi Stadium in Lahore.
It is highly expected that pacer Naseem Shah and vice-captain Shadab Khan will play these games.
Shadab will replace Usman Qadir, while Naseem will play in place of Mohammad Wasim or Mohammad Hasnain.
The 19-year-old Naseem played the first game of the T20I series while Shadab rested in all four games at National Stadium in Karachi.
On the other hand, two teams reached Lahore yesterday and will start training from today. The fifth T20I is scheduled for tomorrow.
Two pitches have been prepared for the matches played on Wednesday, Friday, and Sunday. The pitches look suitable for batting, but the role of spinners will be crucial.