| Player | Runs | Balls | 4s | 6s | SR | Opposition | Ground | Match Date |
|---|---|---|---|---|---|---|---|---|
| Fakhar Zaman | 210 | 156 | 24 | 5 | 134.62 | Zimbabwe | Bulawayo | 20 Jul 2018 |
| Saeed Anwar | 194 | 146 | 22 | 5 | 132.88 | India | 21 May 1997 | |
| Imran Nazir | 160 | 121 | 14 | 8 | 132.23 | Zimbabwe | Kingston | 21 Mar 2007 |
| Sharjeel Khan | 152 | 86 | 16 | 9 | 176.74 | Ireland | 18 Aug 2016 | |
| Younis Khan | 144 | 122 | 8 | 3 | 118.03 | Hong Kong | Colombo (SSC) | 18 Jul 2004 |
| Shoaib Malik | 143 | 127 | 18 | 1 | 112.60 | India | Colombo (RPS) | 25 Jul 2004 |
| Mohammad Hafeez | 140 | 136 | 11 | 3 | 102.94 | Sri Lanka | Sharjah | 22 Dec 2013 |
| Saeed Anwar | 140 | 132 | 14 | 2 | 106.06 | India | Dhaka | 18 Jan 1998 |
| Mohammad Hafeez | 139 | 147 | 13 | 1 | 94.56 | Zimbabwe | Harare | 11 Sep 2011 |
| Ijaz Ahmed | 139 | 84 | 10 | 9 | 165.48 | India | Lahore | 02 Oct 1997 |
| Ijaz Ahmed | 137 | 130 | 12 | 1 | 105.38 | England | Sharjah | 07 Apr 1999 |
| Inzamam-ul-Haq | 137 | 129 | 15 | 0 | 106.20 | New Zealand | Sharjah | 20 Apr 1994 |
| Mohammad Hafeez | 136 | 130 | 9 | 5 | 104.62 | Zimbabwe | Harare | 29 Aug 2013 |
| Salman Butt | 136 | 124 | 14 | 1 | 109.68 | Bangladesh | Karachi | 19 Apr 2008 |
| Saleem Elahi | 135 | 129 | 19 | 0 | 104.65 | South Africa | Port Elizabeth | 11 Dec 2002 |
| Aamer Sohail | 134 | 146 | 13 | 0 | 91.78 | New Zealand | Sharjah | 20 Apr 1994 |
| Salman Butt | 132 | 127 | 15 | 0 | 103.94 | Bangladesh | Lahore | 13 Apr 2008 |
| Ijaz Ahmed | 132 | 103 | 9 | 4 | 128.16 | Zimbabwe | Rawalpindi | 24 Nov 1998 |
| Saeed Anwar | 131 | 141 | 12 | 3 | 92.91 | West Indies | Sharjah | 01 Nov 1993 |
| Haris Sohail | 130 | 129 | 11 | 3 | 100.78 | Australia | 31 Mar 2019 | |
| Salman Butt | 129 | 136 | 12 | 3 | 94.85 | India | Dhaka | 14 Jun 2008 |
| Salman Butt | 129 | 142 | 17 | 0 | 90.85 | India | 11 Nov 2007 | |
| Shoaib Malik | 128 | 126 | 16 | 0 | 101.59 | India | Centurion | 26 Sep 2009 |
| Yasir Hameed | 127 | 154 | 9 | 1 | 82.47 | New Zealand | Rawalpindi | 07 Dec 2003 |
| Basit Ali | 127 | 79 | 12 | 5 | 160.76 | West Indies | Sharjah | 05 Nov 1993 |
| Saeed Anwar | 126 | 99 | 8 | 6 | 127.27 | Sri Lanka | Adelaide | 17 Feb 1990 |
| Shoaib Mohammad | 126 | 155 | 13 | 0 | 81.29 | New Zealand | Wellington | 08 Mar 1989 |
| Babar Azam | 125 | 132 | 7 | 3 | 94.70 | West Indies | Providence | 09 Apr 2017 |
| Shoaib Malik | 125 | 119 | 16 | 1 | 105.04 | India | Karachi | 26 Jun 2008 |
| Ahmed Shehzad | 124 | 140 | 8 | 0 | 88.57 | Sri Lanka | Dubai (DSC) | 20 Dec 2013 |
| Shahid Afridi | 124 | 60 | 17 | 4 | 206.67 | Bangladesh | 21 Jun 2010 | |
| Kamran Akmal | 124 | 125 | 12 | 0 | 99.20 | West Indies | Brisbane | 19 Jan 2005 |
| Ijaz Ahmed | 124 | 87 | 9 | 4 | 142.53 | Bangladesh | Chittagong | 29 Oct 1988 |
| Babar Azam | 123 | 126 | 9 | 1 | 97.62 | West Indies | Sharjah | 02 Oct 2016 |
| Younis Khan | 123 | 117 | 11 | 1 | 105.13 | India | Karachi | 02 Jul 2008 |
| Inzamam-ul-Haq | 123 | 121 | 9 | 4 | 101.65 | India | Lahore | 21 Mar 2004 |
| Zaheer Abbas | 123 | 87 | 15 | 3 | 141.38 | Sri Lanka | Lahore | 29 Mar 1982 |
| Mohammad Hafeez | 122 | 129 | 7 | 4 | 94.57 | Sri Lanka | Sharjah | 18 Dec 2013 |
| Mohammad Hafeez | 122 | 113 | 12 | 2 | 107.96 | Ireland | Dublin | 23 May 2013 |
| Inzamam-ul-Haq | 122 | 102 | 12 | 2 | 119.61 | India | Karachi | 13 Mar 2004 |
| Mohammad Hafeez | 121 | 138 | 7 | 3 | 87.68 | West Indies | Bridgetown | 02 May 2011 |
| Inzamam-ul-Haq | 121 | 113 | 9 | 5 | 107.08 | India | Sharjah | 26 Mar 2000 |
| Babar Azam | 120 | 131 | 8 | 3 | 91.60 | West Indies | Sharjah | 30 Sep 2016 |
| Rameez Raja | 119 | 155 | 16 | 0 | 76.77 | New Zealand | Christchurch | 18 Mar 1992 |
| Javed Miandad | 119 | 77 | 6 | 5 | 154.55 | India | Lahore | 31 Dec 1982 |
| Shoaib Malik | 118 | 110 | 10 | 2 | 107.27 | Hong Kong | Colombo (SSC) | 18 Jul 2004 |
| Inzamam-ul-Haq | 118 | 124 | 10 | 2 | 95.16 | Sri Lanka | Sharjah | 02 Nov 2001 |
| Zaheer Abbas | 118 | 86 | 10 | 4 | 137.21 | India | Multan | 17 Dec 1982 |
| Mohsin Khan | 117 | 118 | 9 | 1 | 99.15 | India | Multan | 17 Dec 1982 |
| Mohammad Rizwan | 115 | 126 | 11 | 0 | 91.27 | Australia | 24 Mar 2019 |
